Recent Publications

2025

• Treatment of Pediatric, Adolescent, and Young Adult Patients With Fusion-Positive Alveolar Rhabdomyosarcoma Infiltrating Regional Lymph Nodes in the European CWS-2002P and RMS 2005 Studies and the Soft Tissue Sarcoma Registry
  Heinz, A. T., et al. Pediatr Blood Cancer 72(3): e31476.

2024

• Significance of fusion status, Oberlin risk factors, local and maintenance treatment in pediatric and adolescent patients with metastatic rhabdomyosarcoma: Data of the European Soft Tissue Sarcoma Registry SoTiSaR
  Heinz, A. T., et al. Pediatr Blood Cancer 71(1): e30707.

• ASO Author Reflections: Surgical Management of Paratesticular Rhabdomyosarcoma
  Martynov, I., et al. Ann Surg Oncol 31(10): 7237-7238.

• Importance of Adequate Surgical Local Control in Fusion-Negative Para-Testicular Rhabdomyosarcoma: Data From the Cooperative Weichteilsarkom Studiengruppe Trials (CWS-96 and CWS-2002P) and the European Soft Tissue Sarcoma Registry (SoTiSaR)
  Martynov, I., et al. Ann Surg Oncol 31(9): 6209-6219.

• Radiotherapy and long-term sequelae in pediatric patients with parameningeal rhabdomyosarcoma: Results of two Cooperative Weichteilsarkom Studiengruppe (CWS) trials and one registry
  Sparber-Sauer, M., et al. Pediatr Blood Cancer 71(1): e30742.

2023

• Clinical characteristics and outcomes for children, adolescents and young adults with "CIC-fused" or "BCOR-rearranged" soft tissue sarcomas: A multi-institutional European retrospective analysis
  Sparber-Sauer, M., et al. Cancer Med 12(13): 14346-14359.

• Second-line treatment of pediatric patients with relapsed rhabdomyosarcoma adapted to initial risk stratification: Data of the European Soft Tissue Sarcoma Registry (SoTiSaR)
  Heinz, A. T., et al. Pediatr Blood Cancer 70(7): e30363.

2022

• Drug sensitivity profiling of 3D tumor tissue cultures in the pediatric precision oncology program INFORM
  Peterziel, H., et al. NPJ Precis Oncol 6(1): 94.

• The future of rhabdomyosarcoma trials
  Sparber-Sauer, M. Lancet Child Adolesc Health 6(8): 510-511.          

• Controversies and challenges in the management of paediatric non-rhabdomyosarcoma soft tissue sarcomas
  Ferrari A, Spunt SL, Sparber-Sauer M, Walterhouse DO, Pajtler KW, Meyer WH, Orbach D, Weiss A.Lancet Child Adolesc Health. 2022 Feb 14:S2352-4642(22)00036-0. doi: 10.1016/S2352-4642(22)00036-0. Online ahead of print.PMID: 35176224 No abstract available.
• Secondary malignant neoplasms after bone and soft tissue sarcomas in children, adolescents, and young adults
  Kube SJ, Blattmann C, Bielack SS, Kager L, Kaatsch P, Kühne T, Sorg B, Kevric M, Jabar S, Hallmen E, Sparber-Sauer M, Klingebiel T, Koscielniak E, Dirksen U, Hecker-Nolting S, Gerß JWO.Cancer. 2022 Feb 23. doi: 10.1002/cncr.34110. Online ahead of print.PMID: 35195899
• Infantile myofibromatosis: Excellent prognosis but also rare fatal progressive disease. Treatment results of five Cooperative Weichteilsarkom Studiengruppe (CWS) trials and one registry
  Sparber-Sauer M, Vokuhl C, Seitz G, Sorg B, Tobias M, von Kalle T, Münter M, Bielack SS, Ladenstein R, Ljungman G, Niggli F, Frühwald M, Loff S, Klingebiel T, Koscielniak E.Pediatr Blood Cancer. 2022 Mar;69(3):e29403. doi: 10.1002/pbc.29403. Epub 2021 Oct 11.PMID: 34636137
• Long-Term Clinical Outcome and Prognostic Factors of Children and Adolescents with Localized Rhabdomyosarcoma Treated on the CWS-2002P Protocol
  Koscielniak E, Blank B, Vokuhl C, Kazanowska B, Ladenstein R, Niggli F, Ljungman G, Handgretinger R, Seitz G, Fuchs J, Fröhlich B, Scheer M, Wessalowski R, Schmid I, Sparber-Sauer M, Klingebiel T.Cancers (Basel). 2022 Feb 11;14(4):899. doi: 10.3390/cancers14040899.PMID: 35205646
• Congenital spindle cell rhabdomyosarcoma: An international cooperative analysis
  Whittle S, Venkatramani R, Schönstein A, Pack SD, Alaggio R, Vokuhl C, Rudzinski ER, Wulf AL, Zin A, Gruver JR, Arnold MA, Merks JHM, Hettmer S, Koscielniak E, Barr FG, Hawkins DS, Bisogno G, Sparber-Sauer M.Eur J Cancer. 2022 Jun;168:56-64. doi: 10.1016/j.ejca.2022.03.022. Epub 2022 Apr 19
• Secondary malignant neoplasms after bone and soft tissue sarcomas in children, adolescents, and young adults
  Kube SJ, Blattmann C, Bielack SS, Kager L, Kaatsch P, Kühne T, Sorg B, Kevric M, Jabar S, Hallmen E, Sparber-Sauer M, Klingebiel T, Koscielniak E, Dirksen U, Hecker-Nolting S, Gerß JWO.Cancer. 2022 May 1;128(9):1787-1800. 
• Infantile myofibromatosis: Excellent prognosis but also rare fatal progressive disease. Treatment results of five Cooperative Weichteilsarkom Studiengruppe (CWS) trials and one registry
  Sparber-Sauer M, Vokuhl C, Seitz G, Sorg B, Tobias M, von Kalle T, Münter M, Bielack SS, Ladenstein R, Ljungman G, Niggli F, Frühwald M, Loff S, Klingebiel T, Koscielniak E.Pediatr Blood Cancer. 2022 Mar;69(3):e29403.
• Long-Term Clinical Outcome and Prognostic Factors of Children and Adolescents with Localized Rhabdomyosarcoma Treated on the CWS-2002P Protocol
  Koscielniak E, Blank B, Vokuhl C, Kazanowska B, Ladenstein R, Niggli F, Ljungman G, Handgretinger R, Seitz G, Fuchs J, Fröhlich B, Scheer M, Wessalowski R, Schmid I, Sparber-Sauer M, Klingebiel T.Cancers (Basel). 2022 Feb 11;14(4):899.
• Long-term results from the multicentric European randomized phase 3 trial CWS/RMS-96 for localized high-risk soft tissue sarcoma in children, adolescents, and young adults
  Sparber-Sauer M, Ferrari A, Kosztyla D, Ladenstein R, Cecchetto G, Kazanowska B, Scarzello G, Ljungman G, Milano GM, Niggli F, Alaggio R, Vokuhl C, Casanova M, Klingebiel T, Zin A, Koscielniak E, Bisogno G.Pediatr Blood Cancer. 2022 Apr 19:e29691.
• Fusion transcripts as liquid biopsy markers in alveolar rhabdomyosarcoma and synovial sarcoma: A report of the Cooperative Weichteilsarkom Studiengruppe (CWS)
  Stegmaier S, Sparber-Sauer M, Aakcha-Rudel E, Münch P, Reeh T, Feuchtgruber S, Hallmen E, Blattmann C, Bielack S, Klingebiel T, Koscielniak E.Pediatr Blood Cancer. 2022 Mar 26:e29652.
• No Improvement of Survival for Alveolar Rhabdomyosarcoma Patients After HLA-Matched Versus -Mismatched Allogeneic Hematopoietic Stem Cell Transplantation Compared to Standard-of-Care Therapy
  Schober SJ, Hallmen E, Reßle F, Gassmann H, Prexler C, Wawer A, von Luettichau I, Ladenstein R, Kazanowska B, Ljungman G, Niggli F, Lohi O, Hauer J, Gruhn B, Klingebiel T, Bader P, Burdach S, Lang P, Sparber-Sauer M, Koscielniak E, Thiel U.Front Oncol. 2022 May 10;12:878367

2021

• Rationale for the use of tyrosine kinase inhibitors in the treatment of paediatric desmoid-type fibromatosis. Sparber-Sauer M, Orbach D, Navid F, Hettmer S, Skapek S, Corradini N, Casanova M, Weiss A, Schwab M, Ferrari A.Br J Cancer. 2021 May;124(10):1637-1646. doi: 10.1038/s41416-021-01320-1. Epub 2021 Mar 15.PMID: 33723397 Review.
• Rhabdomyosarcoma of the female genitourinary tract: Primary and relapsed disease in infants and older children. Treatment results of five Cooperative Weichteilsarkom Studiengruppe (CWS) trials and one registry. Sparber-Sauer M, Matle M, Vokuhl C, Hallmen E, von Kalle T, Münter M, Timmermann B, Bielack SS, Klingebiel T, Koscielniak E, Seitz G; CWS Study Group.Pediatr Blood Cancer. 2021 Apr;68(4):e28889. doi: 10.1002/pbc.28889. Epub 2021 Jan 12.PMID: 33438323 Clinical Trial.
• Genetic testing and surveillance in infantile myofibromatosis: a report from the SIOPE Host Genome Working Group. Hettmer S, Dachy G, Seitz G, Agaimy A, Duncan C, Jongmans M, Hirsch S, Kventsel I, Kordes U, de Krijger RR, Metzler M, Michaeli O, Nemes K, Poluha A, Ripperger T, Russo A, Smetsers S, Sparber-Sauer M, Stutz E, Bourdeaut F, Kratz CP, Demoulin JB.Fam Cancer. 2021 Oct;20(4):327-336. doi: 10.1007/s10689-020-00204-2. Epub 2020 Sep 5.PMID: 32888134 Free PMC article.
• Children with progressive and relapsed pleuropulmonary blastoma: A European collaborative analysis. Sparber-Sauer M, Tagarelli A, Seitz G, Sorg B, Bien E, Bel-Ami T, Pourtsidis A, Lopez Almaraz R, Koscielniak E, Ferrari A, Orbach D, Bisogno G; EXPeRT and CWS Study Groups.Pediatr Blood Cancer. 2021 Dec;68(12):e29268. doi: 10.1002/pbc.29268. Epub 2021 Sep 5.PMID: 34486213
• European guideline for imaging in paediatric and adolescent rhabdomyosarcoma - joint statement by the European Paediatric Soft Tissue Sarcoma Study Group, the Cooperative Weichteilsarkom Studiengruppe and the Oncology Task Force of the European Society of Paediatric Radiology. van Ewijk R, Schoot RA, Sparber-Sauer M, Ter Horst SAJ, Jehanno N, Borgwardt L, de Keizer B, Merks JHM, de Luca A, McHugh K, von Kalle T, Schäfer JF, van Rijn RR; Cooperative Weichteilsarkom Studiengruppe Imaging Group, the European Society of Paediatric Radiology Oncology Task Force and the European Paediatric Soft Tissue Sarcoma Study Group Imaging Committee.Pediatr Radiol. 2021 Sep;51(10):1940-1951. doi: 10.1007/s00247-021-05081-0. Epub 2021 Jun 17.PMID: 34137936 Free PMC article.
• Extraskeletal Ewing sarcoma in children, adolescents, and young adults. An analysis of three prospective studies of the Cooperative Weichteilsarkomstudiengruppe (CWS). Koscielniak E, Sparber-Sauer M, Scheer M, Vokuhl C, Kazanowska B, Ladenstein R, Niggli F, Ljungman G, Paulussen M, Bielack SS, Seitz G, Fuchs J, Hallmen E, Klingebiel T, On Behalf Of The Cws Study Group.Pediatr Blood Cancer. 2021 Oct;68(10):e29145. doi: 10.1002/pbc.29145. Epub 2021 Jun 5.PMID: 34089219

2017

• Childhood cancer predisposition syndromes-A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology
  Ripperger, T., et al. Am J Med Genet A 173(4): 1017-1037.