Publikationen

Histogram Profiling of Postcontrast T1-Weighted MRI Gives Valuable Insights into Tumor Biology and Enables Prediction of Growth Kinetics and Prognosis in Meningiomas.
Gihr GA, Horvath-Rizea D, Kohlhof-Meinecke P, Ganslandt O, Henkes H, Richter C, Hoffmann KT, Surov A, Schob S.
Transl Oncol. 2018 Aug;11(4):957-961. doi: 10.1016/j.tranon.2018.05.009. Epub 2018 Jun 18.
PMID: 29909365
 
The value of whole lesion ADC histogram profiling to differentiate between morphologically indistinguishable ring enhancing lesions-comparison of glioblastomas and brain abscesses.
Horvath-Rizea D, Surov A, Hoffmann KT, Garnov N, Vörkel C, Kohlhof-Meinecke P, Ganslandt O, Bäzner H, Gihr GA, Kalman M, Henkes E, Henkes H, Schob S.
Oncotarget. 2018 Apr 6;9(26):18148-18159. doi: 10.18632/oncotarget.24454. eCollection 2018 Apr 6.
PMID: 29719596

Diffusion Profiling via a Histogram Approach Distinguishes Low-grade from High-grade Meningiomas, Can Reflect the Respective Proliferative Potential and Progesterone Receptor Status.
Gihr GA, Horvath-Rizea D, Garnov N, Kohlhof-Meinecke P, Ganslandt O, Henkes H, Meyer HJ, Hoffmann KT, Surov A, Schob S.
Mol Imaging Biol. 2018 Aug;20(4):632-640. doi: 10.1007/s11307-018-1166-2.
PMID: 29392542

Concomitant Retroperitoneal and Subarachnoid Hemorrhage Due to Segmental Arterial Mediolysis : Case Report and Review of the Literature.
Hellstern V, Aguilar Pérez M, Kohlhof-Meinecke P, Bäzner H, Ganslandt O, Henkes H.
Clin Neuroradiol. 2018 Sep;28(3):445-450. doi: 10.1007/s00062-017-0641-5. Epub 2017 Nov 3. Review. No abstract available.
PMID: 29101412

FGFR1:TACC1 fusion is a frequent event in molecularly defined extraventricular neurocytoma.
Sievers P, Stichel D, Schrimpf D, Sahm F, Koelsche C, Reuss DE, Wefers AK, Reinhardt A, Huang K, Ebrahimi A, Hou Y, Pajtler KW, Pfister SM, Hasselblatt M, Stummer W, Schick U, Hartmann C, Hagel C, Staszewski O, Reifenberger G, Beschorner R, Coras R, Keyvani K, Kohlhof P, Diomedi-Camassei F, Herold-Mende C, Giangaspero F, Rushing E, Giannini C, Korshunov A, Jones DTW, von Deimling A.
Acta Neuropathol. 2018 Aug;136(2):293-302. doi: 10.1007/s00401-018-1882-3. Epub 2018 Jul 5.
PMID: 29978331

Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations.
Reinhardt A, Stichel D, Schrimpf D, Sahm F, Korshunov A, Reuss DE, Koelsche C, Huang K, Wefers AK, Hovestadt V, Sill M, Gramatzki D, Felsberg J, Reifenberger G, Koch A, Thomale UW, Becker A, Hans VH, Prinz M, Staszewski O, Acker T, Dohmen H, Hartmann C, Mueller W, Tuffaha MSA, Paulus W, Heß K, Brokinkel B, Schittenhelm J, Monoranu CM, Kessler AF, Loehr M, Buslei R, Deckert M, Mawrin C, Kohlhof P, Hewer E, Olar A, Rodriguez FJ, Giannini C, NageswaraRao AA, Tabori U, Nunes NM, Weller M, Pohl U, Jaunmuktane Z, Brandner S, Unterberg A, Hänggi D, Platten M, Pfister SM, Wick W, Herold-Mende C, Jones DTW, von Deimling A, Capper D.
Acta Neuropathol. 2018 Aug;136(2):273-291. doi: 10.1007/s00401-018-1837-8. Epub 2018 Mar 21.
PMID: 29564591

DNA methylation-based classification of central nervous system tumours.
Capper D, Jones DTW, Sill M, Hovestadt V, Schrimpf D, Sturm D, Koelsche C, Sahm F, Chavez L, Reuss DE, Kratz A, Wefers AK, Huang K, Pajtler KW, Schweizer L, Stichel D, Olar A, Engel NW, Lindenberg K, Harter PN, Braczynski AK, Plate KH, Dohmen H, Garvalov BK, Coras R, Hölsken A, Hewer E, Bewerunge-Hudler M, Schick M, Fischer R, Beschorner R, Schittenhelm J, Staszewski O, Wani K, Varlet P, Pages M, Temming P, Lohmann D, Selt F, Witt H, Milde T, Witt O, Aronica E, Giangaspero F, Rushing E, Scheurlen W, Geisenberger C, Rodriguez FJ, Becker A, Preusser M, Haberler C, Bjerkvig R, Cryan J, Farrell M, Deckert M, Hench J, Frank S, Serrano J, Kannan K, Tsirigos A, Brück W, Hofer S, Brehmer S, Seiz-Rosenhagen M, Hänggi D, Hans V, Rozsnoki S, Hansford JR, Kohlhof P, Kristensen BW, Lechner M, Lopes B, Mawrin C, Ketter R, Kulozik A, Khatib Z, Heppner F, Koch A, Jouvet A, Keohane C, Mühleisen H, Mueller W, Pohl U, Prinz M, Benner A, Zapatka M, Gottardo NG, Driever PH, Kramm CM, Müller HL, Rutkowski S, von Hoff K, Frühwald MC, Gnekow A, Fleischhack G, Tippelt S, Calaminus G, Monoranu CM, Perry A, Jones C, Jacques TS, Radlwimmer B, Gessi M, Pietsch T, Schramm J, Schackert G, Westphal M, Reifenberger G, Wesseling P, Weller M, Collins VP, Blümcke I, Bendszus M, Debus J, Huang A, Jabado N, Northcott PA, Paulus W, Gajjar A, Robinson GW, Taylor MD, Jaunmuktane Z, Ryzhova M, Platten M, Unterberg A, Wick W, Karajannis MA, Mittelbronn M, Acker T, Hartmann C, Aldape K, Schüller U, Buslei R, Lichter P, Kool M, Herold-Mende C, Ellison DW, Hasselblatt M, Snuderl M, Brandner S, Korshunov A, von Deimling A, Pfister SM.
Nature. 2018 Mar 22;555(7697):469-474. doi: 10.1038/nature26000. Epub 2018 Mar 14.
PMID: 29539639

Diagnostic tools in the differential diagnosis of giant cell-rich lesions of bone at biopsy.
Rehkämper J, Steinestel K, Jeiler B, Elges S, Hekeler E, Huss S, Sperveslage J, Hardes J, Streitbürger A, Gosheger G, Wardelmann E, Baumhoer D, Trautmann M, Hartmann W.
Oncotarget. 2018 Jul 10;9(53):30106-30114. doi: 10.18632/oncotarget.25725. eCollection 2018 Jul 10.
PMID: 30046391

Prenatal Diagnosis and Clinical Course of a Patent Urachus Associated with an Allantoic Cord Cyst and a Giant Umbilical Cord.
Tekesin I, Küper-Steffen R.
Ultrasound Int Open. 2018 Sep;4(3):E104-E105. doi: 10.1055/a-0633-3879. Epub 2018 Sep 24. No abstract available.
PMID: 30255165

Resection of benign side-branch intraductal papillary mucinous neoplasm of the pancreas-is long term follow-up indicated?: A case report and review of the literature.
Fritz S, Küper-Steffen R, Feilhauer K, Sommer CM, Richter GM, Hennig R, Köninger J.
Medicine (Baltimore). 2018 Feb;97(7):e9894. doi: 10.1097/MD.0000000000009894.
PMID: 29443760

Combined Targeted Resequencing of Cytosine DNA Methylation and Mutations of DNA Repair Genes with Potential Use for Poly(ADP-Ribose) Polymerase 1 Inhibitor Sensitivity Testing.
Grimm C, Fischer A, Farrelly AM, Kalachand R, Castiglione R, Wasserburger E, Hussong M, Schultheis AM, Altmüller J, Thiele H, Reinhardt HC, Hauschulz K, Hennessy BT, Herwig R, Lienhard M, Buettner R, Schweiger MR.
J Mol Diagn. 2018 Dec 19. pii: S1525-1578(18)30247-2. doi: 10.1016/j.jmoldx.2018.10.007. [Epub ahead of print]
PMID: 30576872

Comparison of the genomic background of MET-altered carcinomas of the lung: biological differences and analogies.
Castiglione R, Alidousty C, Holz B, Wagener S, Baar T, Heydt C, Binot E, Zupp S, Kron A, Wolf J, Merkelbach-Bruse S, Reinhardt HC, Buettner R, Schultheis AM.
Mod Pathol. 2018 Nov 20. doi: 10.1038/s41379-018-0182-8. [Epub ahead of print]
PMID: 30459450

The Cdkn1a^SUPER Mouse as a Tool to Study p53-Mediated Tumor Suppression.
Torgovnick A, Heger JM, Liaki V, Isensee J, Schmitt A, Knittel G, Riabinska A, Beleggia F, Laurien L, Leeser U, Jüngst C, Siedek F, Vogel W, Klümper N, Nolte H, Wittersheim M, Tharun L, Castiglione R, Krüger M, Schauss A, Perner S, Pasparakis M, Büttner R, Persigehl T, Hucho T, Herter-Sprie GS, Schumacher B, Reinhardt HC.
Cell Rep. 2018 Oct 23;25(4):1027-1039.e6. doi: 10.1016/j.celrep.2018.09.079.
PMID: 30355482

Clonal dynamics towards the development of venetoclax resistance in chronic lymphocytic leukemia.
Herling CD, Abedpour N, Weiss J, Schmitt A, Jachimowicz RD, Merkel O, Cartolano M, Oberbeck S, Mayer P, Berg V, Thomalla D, Kutsch N, Stiefelhagen M, Cramer P, Wendtner CM, Persigehl T, Saleh A, Altmüller J, Nürnberg P, Pallasch C, Achter V, Lang U, Eichhorst B, Castiglione R, Schäfer SC, Büttner R, Kreuzer KA, Reinhardt HC, Hallek M, Frenzel LP, Peifer M.
Nat Commun. 2018 Feb 20;9(1):727. doi: 10.1038/s41467-018-03170-7.
PMID: 29463802

Hormone receptors analysis in idiopathic progressive subglottic stenosis.
Fiz I, Bittar Z, Piazza C, Koelmel JC, Gatto F, Ferone D, Fiz F, Di Dio D, Bosse A, Peretti G, Sittel C.
Laryngoscope. 2018 Feb;128(2):E72-E77. doi: 10.1002/lary.26931. Epub 2017 Oct 9.
PMID: 28990664

Predictors of recurrence after surgical treatment of idiopathic progressive subglottic stenosis.
Fiz I, Koelmel JC, Piazza C, Fiz F, Di Dio D, Bittar Z, Peretti G, Sittel C.
Acta Otorhinolaryngol Ital. 2018 Oct;38(5):417-423. doi: 10.14639/0392-100X-1872.
PMID: 30498269

S. Jenner, D. Techel:
Development of a gLCR based KRAS Mutation Detection Approach and its Comparison with other Screening Methods.
Tumor Biology, DOI 10.1007/s13277-015-3323-4 (2015)

Melanotic Tumors of the Nervous System are Characterized by Distinct Mutational, Chromosomal and Epigenomic Profiles.
Koelsche C, Hovestadt V, Jones DT, Capper D, Sturm D, Sahm F, Schrimpf D, Adeberg S, Böhmer K, Hagenlocher C, Mechtersheimer G, Kohlhof P, Mühleisen H, Beschorner R, Hartmann C, Braczynski AK, Mittelbronn M, Buslei R, Becker A, Grote A, Urbach H, Staszewski O, Prinz M, Hewer E, Pfister SM, von Deimling A, Reuss DE.
Brain Pathol. 2014 Nov 17. doi: 10.1111/bpa.12228. [Epub ahead of print]

A new spruelike disease as a cause of severe diarrhea
Halevy D, Teeuwen U, Kohlhof P.
Dtsch Med Wochenschr. 2014 Nov;139(45):2290-3. doi: 10.1055/s-0034-1387342. Epub 2014 Oct 28.

The embryonic stem cell factor UTF1 serves as a reliable diagnostic marker for germinomas.
Pantazis G, Harter PN, Capper D, Kohlhof P, Mittelbronn M, Schittenhelm J.
Pathology. 2014 Apr;46(3):225-9.

BRAF-mutated pleomorphic xanthoastrocytoma is associated with temporal location, reticulin fiber deposition and CD34 expression.
Koelsche C, Sahm F, Wöhrer A, Jeibmann A, Schittenhelm J, Kohlhof P, Preusser M, Romeike B, Dohmen-Scheufler H, Hartmann C, Mittelbronn M, Becker A, von Deimling A, Capper D.
Brain Pathol. 2014 Apr;24(3):221-9. doi: 10.1111/bpa.12111. Epub 2014 Jan 29.

Development of a DUSP9 Methylation Screening Assay.
Stefan Jenner, Klaus Herrmann Wiedorn, Dieter Techel. Pathol. Oncol. Res.20 (2) April 2014.

Middle ear salivary gland choristoma related to branchio-oto-renal syndrome diagnosed by array-CGH.
Amrhein P, Sittel C, Spaich C, Kohlhase J, Boppert R, Kohlhof P, Koitschev A.
HNO. 2014 May;62(5):374-7.

• Hann A, Schupp C, Ohmer M, Burkhardt C, Pöpperl G, Bosse A, Zoller WG: Grenzen der apparativ-diagnostischen Verfahren bei der Suche nach einem neuroendokrinen Tumor. Poster
• Bittar Z et.al.: Clinicopathologic features of ductal carcinoma in situ in young women with an emphasis on molecular subtype. Hum Pathol. 2013 Nov; 44(11):2487-93
• Bittar Z et.al.: Lymphoepithelioma-like carcinoma of the stomach: a case report and review of the literature. Diagn Pathol. 2013 Nov 4; 8(1):184

Potapov EV, Dranishnikov N, Morawietz L, Stepanenko A, Rezai S, Blechschmidt C, Lehmkuhl HB, Weng Y, Pasic M, Hübler M, Hetzer R, Krabatsch T: Arterial wall histology in chronic pulsatile-flow and continuous-flow device circulatory support. J Heart Lung Transplant. 2012 Nov; 31(11):1171-6. doi: 10.1016/j.healun.2012.08.013. Epub 2012 Sep 18

Pauly S, Morawietz L, Krüger D, Strube P, Scheibel M: Histopathologic evaluation of passive stabilizers in shoulder instability. J Shoulder Elbow Surg. 2012 Sep 12. doi:pii: S1058-2746(12)00295-9. 10.1016/ j.jse.2012.07.006. [Epub ahead of print]

Komoda S, Komoda T, Knosalla C, Pavel ME, Morawietz L, von Weikersthal LF, Lehmkuhl HB, Hetzer R: A giant neuroendocrine tumor of the thymus gland causing superior vena cava syndrome. Gen Thorac Cardiovasc Surg. 2012 Dec; 60(12):863-7. doi: 10.1007/s11748-012-0104-5. Epub 2012 May 30

Krüger JP, Endres M, Neumann K, Stuhlmüller B, Morawietz L, Häupl T, Kaps C: Chondrogenic differentiation of human subchondral progenitor cells is affected by synovial fluid from donors with osteoarthritis or rheumatoid arthritis. J Orthop Surg Res. 2012 Mar 13; 7:10. doi: 10.1186/1749-799X-7-10

Freymann U, Endres M, Neumann K, Scholman HJ, Morawietz L, Kaps C: Expanded human meniscus-derived cells in 3-D polymer-hyaluronan scaffolds for meniscus repair. Acta Biomater. 2012 Feb; 8(2):677-85. doi: 10.1016/j.actbio.2011.10.007. Epub 2011 Oct 11.

Hekeler E, Zoller WG, Wiedorn KH, Bosse A: Der Wandel der Pathologie in der Ära der personalisierten Medizin. Dtsch. Med. Wochenschr. 2012; 137

Trimborn M, Endres M, Bommer C, Janke U, Krüger JP, Morawietz L, Kreuz PC, Kaps C: Karyotyping of human chondrocytes in scaffold-assisted cartilage tissue engineering. Acta Biomater. 2012 Apr; 8(4):1519-29. doi: 10.1016/ j.actbio.2011.12.024. Epub 2011 Dec 20.

A. Bosse
Medizintechnik – Aktuelle Aspekte.
Wehrmedizinische Monatsschrift 2009; 53, 4: 99-102

Beschorner R, Mittelbronn M, Mugler M, Meyermann R, Schittenhelm J.
Immunohistochemical analysis of CDX2 expression in normal choroid plexus epithelium and choroid plexus tumors.
Histol Histopathol. 2009 Dec;24(12):1507-14.

Orakcioglu B, Schramm P, Kohlhof P, Aschoff A, Unterberg A, Halatsch ME.
Characteristics of thoracolumbar intramedullary subependymomas.
J Neurosurg Spine. 2009 Jan;10(1):54-9.

Seiz M, Kohlhof P, Brockmann MA, Neumaier-Probst E, Hermes P, Von Deimling A, Vajkoczy P, Schmieder K, Tuettenberg J.
First experiences with low-dose anti-angiogenic treatment in gliomatosis cerebri with signs of angiogenic activity.
Anticancer Res. 2009 Aug;29(8):3261-7

Mogler C, Kohlhof P, Penzel R, Grenacher L, Haag GM, Schirmacher P, Mueller W.
A primary malignant ependymoma of the abdominal cavity: a case report and review of the literature.
Virchows Arch. 2009 Apr;454(4):475-8. Epub 2009 Feb 24.