Whole-brain radiotherapy or autologous stem-cell transplantation as consilodation strategies after high-dose methotrexate-based chemoimmunotherapy in patients with primary CNS lymphoma: results of the second randomisation of the International Extranodal Lymphoma Study Group-32 phase 3 trial. Ferreri AJM, Cwynarski K, Pulczynski E, Fox CP, Schorb E, La Rosée P, Binder M, Fabbri A, Torri V, Minacapelli E, Falautano M, Ilariucci F, Ambrosetti A, Roth A, Hemmaway C, Johnson P, Linton KM, Pukrop T, Sønderskov Gørløv J, Balzarotti M, Hess G, Keller U, Stilgenbauer S, Panse J, Tucci A, Orsucci L, Pisani F, Levis A, Krause SW, Schmoll HJ, Hertenstein B, Rummel M, Smith J, Pfreundschuh M, Cabras G, Angrilli F, Ponzoni M, Deckert M, Politi LS, Finke J, Reni M, Cavalli F, Zucca E, Illerhaus G; International Extranodal Lymphoma Study Group (IELSG). Lancet Haematol. 2017;4(11):e510-e523.
High-dose chemotherapy with autologous haematopoietic stem cell support for relapsed or refractory primary CNS lymphoma: a prospective multicentre trial by the German Cooperative PCNSL study group. Kasenda B, Ihorst G, Schroers R, Korfel A, Schmidt-Wolf I, Egerer G, von Baumgarten L, Röth A, Bloehdorn J, Möhle R, Binder M, Keller U, Lamprecht M, Pfreundschuh M, Valk E, Fricker H, Schorb E, Fritsch K, Finke J, Illerhaus G. Leukemia. 2017; 31(12):2623-2629.
High-dose thiotepa-based chemotherapy with autologous stem cell support in elderly patients with primary central nervous system lymphoma: a European retrospective study. Schorb E, Fox CP, Fritsch K, Isbell L, Neubauer A, Tzalavras A, Witherall R, Choquet S, Kuittinen O, De-Silva D, Cwynarski K, Houillier C, Hoang-Xuan K, Touitou V, Cassoux N, Marolleau JP, Tamburini J, Houot R, Delwail V, Illerhaus G, Soussain C, Kasenda B. Bone Marrow Transplant. 2017, 52(8):1113-1119.
High-dose methotrexate-based immuno-chemotherapy for elderly primary CNS lymphoma patients (PRIMAIN study). Fritsch K, Kasenda B, Schorb E, Hau P, Bloehdorn J, Möhle R, Löw S, Binder M, Atta J, Keller U, Wolf HH, Krause SW, Heß G, Naumann R, Sasse S, Hirt C, Lamprecht M, Martens U, Morgner A, Panse J, Frickhofen N, Röth A, Hader C, Deckert M, Fricker H, Ihorst G, Finke J, Illerhaus G. Leukemia. 2017; 31(4):846-852.
High-dose chemotherapy with autologous haemopoietic stem cell transplantation for newly diagnosed primary CNS lymphoma: a prospective, single-arm, phase 2 trial. Illerhaus G, Kasenda B, Ihorst G, Egerer G, Lamprecht M, Keller U, Wolf H-H, Hirt C, Stilgenbauer S, Binder M, Hau P, Edinger M, Frickhofen N, Bentz M, Möhle R, Röth A, Pfreundschuh M, von Baumgarten L, Deckert M, Hader C, Fricker H, Valk E, Schorb E, Fritsch K, Finke J. The Lancet Haematology 2016; published online: 12 July 2016.
Extranodal diffuse large B-cell lymphoma (DLBCL) and primary mediastinal B-cell lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Vitolo U, Seymour JF, Martelli M, Illerhaus G, Illidge T, Zucca E, Campo E, Ladetto M, Committee EG. Annals of oncology: official journal of the European Society for Medical Oncology / ESMO 2016. ePub 04 July2016.
Chemoimmunotherapy with methotrexate, cytarabine, thiotepa, and rituximab (MATRix regimen) in patients with primary CNS lymphoma: results of the first randomisation of the International Extranodal Lymphoma Study Group-32 (IELSG32) phase 2 trial. Ferreri AJ, Cwynarski K, Pulczynski E, Ponzoni M, Deckert M, Politi LS, Torri V, Fox CP, Rosee PL, Schorb E, Ambrosetti A, Roth A, Hemmaway C, Ferrari A, Linton KM, Ruda R, Binder M, Pukrop T, Balzarotti M, Fabbri A, Johnson P, Gorlov JS, Hess G, Panse J, Pisani F, Tucci A, Stilgenbauer S, Hertenstein B, Keller U, Krause SW, Levis A, Schmoll HJ, Cavalli F, Finke J, Reni M, Zucca E, Illerhaus G. The Lancet Haematology 2016; 3(5):e217-227.
High-dose chemotherapy and autologous stem cell transplant compared with conventional chemotherapy for consolidation in newly diagnosed primary CNS lymphoma-a randomized phase III trial (MATRix). Schorb E, Finke J, Ferreri AJ, Ihorst G, Mikesch K, Kasenda B, Fritsch K, Fricker H, Burger E, Grishina O, Valk E, Zucca E, Illerhaus G. BMC cancer 2016; 16(1):282.
The role of autologous stem cell transplantation in primary central nervous system lymphoma. Ferreri AJ, Illerhaus G. Blood 2016; 127(13):1642-1649.
Targetable genetic features of primary testicular and primary central nervous system lymphomas. Chapuy B, Roemer MG, Stewart C, Tan Y, Abo RP, Zhang L, Dunford AJ, Meredith DM, Thorner AR, Jordanova ES, Liu G, Feuerhake F, Ducar MD, Illerhaus G, Gusenleitner D, Linden EA, Sun HH, Homer H, Aono M, Pinkus GS, Ligon AH, Ligon KL, Ferry JA, Freeman GJ, van Hummelen P, Golub TR, Getz G, Rodig SJ, de Jong D, Monti S, Shipp MA. Blood 2016; 127(7):869-881.
Outcomes for HIV-positive patients with primary central nervous system lymphoma after high-dose chemotherapy and auto-SCT. O'Neill A, Mikesch K, Fritsch K, Kasenda B, Banerjee L, Burns F, Zakout G, Johnston R, Illerhaus G, Cwynarski K. Bone marrow transplantation 2015; 50(7):999-1000.
Prognosis after high-dose chemotherapy followed by autologous stem-cell transplantation as first-line treatment in primary CNS lymphoma--a long-term follow-up study. Kasenda B, Schorb E, Fritsch K, Finke J, Illerhaus G. Ann Oncol. 2015 Mar;26(3):608-11. PMID: 25725080
First-line treatment and outcome of elderly patients with primary central nervous system lymphoma (PCNSL)--a systematic review and individual patient data meta-analysis. Kasenda B, Ferreri AJ, Marturano E, Forst D, Bromberg J, Ghesquieres H, Ferlay C, Blay JY, Hoang-Xuan K, Pulczynski EJ, Fossa A, Okoshi Y, Chiba S, Fritsch K, Omuro A, O'Neill BP, Bairey O, Schandelmaier S, Gloy V, Bhatnagar N, Haug S, Rahner S, Batchelor TT, Illerhaus G, Briel M. Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2015; 26(7):1305-1313.
The trabectome as treatment option in secondary glaucoma due to intraocular lymphoma. van Oterendorp C, Ness T, Illerhaus G, Neuburger M, Jordan JF. J Glaucoma. 2014 Sep;23(7):482-4. PMID: 25170980
Therapie primär zerebraler Lymphome. Illerhaus G. Dtsch Med Wochenschr. 2013 Dec;138(49):2515-8. PMID: 24281958
Long-term cognitive function, neuroimaging, and quality of life in primary CNS lymphoma. Doolittle ND, Korfel A, Lubow MA, Schorb E, Schlegel U, Rogowski S, Fu R, Dósa E, Illerhaus G, Kraemer DF, Muldoon LL, Calabrese P, Hedrick N, Tyson RM, Jahnke K, Maron LM, Butler RW, Neuwelt EA. Neurology. 2013 Jul 2;81(1):84-92. PMID: 23685932
Prognosis of patients with primary central nervous system lymphoma after high-dose chemotherapy followed by autologous stem cell transplantation. Schorb E, Kasenda B, Atta J, Kaun S, Morgner A, Hess G, Elter T, von Bubnoff N, Dreyling M, Ringhoffer M, Krause SW, Derigs G, Klimm B, Niemann D, Fritsch K, Finke J, Illerhaus G. Haematologica. 2013 May;98(5):765-70. PMID: 23300179
18F-FDG PET is an independent outcome predictor in primary central nervous system lymphoma. Kasenda B, Haug V, Schorb E, Fritsch K, Finke J, Mix M, Hader C, Weber WA, Illerhaus G, Meyer PT. J Nucl Med. 2013 Feb;54(2):184-91. PMID: 23249539
Phase II study of central nervous system (CNS)-directed chemotherapy including high-dose chemotherapy with autologous stem cell transplantation for CNS relapse of aggressive lymphomas. Korfel A, Elter T, Thiel E, Hänel M, Möhle R, Schroers R, Reiser M, Dreyling M, Eucker J, Scholz C, Metzner B, Röth A, Birkmann J, Schlegel U, Martus P, Illerhaus G, Fischer L. Haematologica. 2013 Mar;98(3):364-70. PMID:23242601
Central nervous system recurrence of systemic lymphoma in the era of stem cell transplantation - an International Primary Central Nervous System Lymphoma Study Group project. Bromberg JE, Doorduijn JK, Illerhaus G, Jahnke K, Korfel A, Fischer L, Fritsch K, Kuittinen O, Issa S, van Montfort C, van den Bent MJ. Haematologica. 2013 May;98(5):808-13. PMID: 23144196
Role of chemotherapy additional to high-dose methotrexate for primary central nervous system lymphoma (PCNSL). Bergner N, Monsef I, Illerhaus G, Engert A, Skoetz N. Cochrane Database Syst Rev. 2012 Nov 14;11. PMID: 23152274 (Review)
Rational administration schedule for high-dose methotrexate in patients with primary central nervous system lymphoma. Joerger M, Huitema AD, Illerhaus G, Ferreri AJ. Leuk Lymphoma. 2012 Oct;53(10):1867-75. PMID: 22530664 (Review)
Prognosis after high-dose chemotherapy followed by autologous stem-cell transplantation as first-line treatment in primary CNS lymphoma - a long-term follow-up study. Kasenda B, Schorb E, Fritsch K, Finke J, Illerhaus G. Ann Oncol. 2012 Oct;23(10):2670-5. PMID: 22473593
The prognostic value of serum methotrexate area under curve in elderly primary CNS lymphoma patients. Kasenda B, Rehberg M, Thürmann P, Franzem M, Veelken H, Fritsch K, Schorb E, Finke J, Lebiedz D, Illerhaus G. Ann Hematol. 2012 Aug;91(8):1257-64. PMID: 22456893
Modern concepts in the biology, diagnosis, differential diagnosis and treatment of primary central nervous system lymphoma. Deckert M, Engert A, Brück W, Ferreri AJ, Finke J, Illerhaus G , Klapper W, Korfel A, Küppers R, Maarouf M, Montesinos-Rongen M, Paulus W, Schlegel U, Lassmann H, Wiestler OD, Siebert R, Deangelis LM. Leukemia. 2011Dec;25(12):1797-807. PMID: 21818113
High-dose methotrexate in patients with primary central nervous system lymphoma: does drug exposure really matter? Joerger M, Huitema AD, Illerhaus G , Ferreri AJ. Leuk Lymphoma. 2011 Oct;52(10):1825-7. PMID: 21657964
PCNSL: biomarker better than biopsy? Illerhaus G , Batchelor T. Blood. 2011 Mar 17;117(11):2987-9. PMID: 21415274
Immunochemotherapy with rituximab, methotrexate, procarbazine, and lomustine for primary CNS lymphoma (PCNSL) in the elderly. Fritsch K, Kasenda B, Hader C, Nikkhah G, Prinz M, Haug V, Haug S, Ihorst G, Finke J, Illerhaus G. Ann Oncol. 2011 Sep;22(9):2080-5. PMID: 21303800
Whole-brain radiotherapy in primary CNS lymphoma. Ferreri AJ, Deangelis L, Illerhaus G , O'Neill BP, Reni M, Soussain C, Yahalom J. Lancet Oncol. 2011 Feb;12(2):118-9. PMID: 21277546
Modern concepts in the biology, diagnosis, differential diagnosis and treatment of primary central nervous system lymphoma. Deckert M, Engert A, Brück W, Ferreri AJ, Finke J, Illerhaus G, Klapper W, Korfel A, Küppers R, Maarouf M, Montesinos-Rongen M, Paulus W, Schlegel U, Lassmann H, Wiestler OD, Siebert R, DeAngelis LM. Leukemia. 2011 Dec;25(12):1797-807. PMID: 21818113 (Review)
High-dose methotrexate in patients with primary central nervous system lymphoma: does drug exposure really matter? Joerger M, Huitema AD, Illerhaus G, Ferreri AJ. Leuk Lymphoma. 2011 Oct;52(10):1825-7. PMID: 21657964
Primary CNS lymphoma - radiation free salvage therapy by second autologous stem cell transplantation. Kasenda B, Schorb E, Fritsch K, Hader C, Finke J, Illerhaus G. Biol Blood Marrow Transplant. 2011 Feb;17(2):281-3. PMID: 21093600.
Flows and flaws in primary central nervous system lymphoma. International Extranodal Lymphoma Study Group. Ferreri AJ, Illerhaus G , Zucca E, Cavalli F. Nat Rev Clin Oncol. 2010, Aug;7(8). PMID: 20700952
High-dose methotrexate combined with procarbazine and CCNU for primary CNS lymphoma in the elderly: results of a prospective pilot and phase II study. Illerhaus G , Marks R, Müller F, Ihorst G, Feuerhake F, Deckert M, Ostertag C, Finke J. Ann Oncol. 2009 Feb;20(2):319-25. PMID: 18953065
CNS Hodgkin lymphoma. Gerstner ER, Abrey LE, Schiff D, Ferreri AJ, Lister A, Montoto S, Tsang R, Thiel E, Graus F, Behringer D, Illerhaus G , Weaver S, Wen P, Voloschin A, Harris NL, Batchelor TT. Blood. 2008 Sep 1;112(5):1658-61. PMID: 18591379
High-dose chemotherapy and autologous stem-cell transplantation without consolidating radiotherapy as first-line treatment for primary lymphoma of the central nervous system. Illerhaus G, Muller F, Feuerhake F, Schäfer AO, Ostertag C, Finke J. Haematologica. 2008 Jan;93(1):147-8. PMID: 18166803
Brain parenchyma involvement as isolated central nervous system (CNS) relapse of systemic non-Hodgkin lymphoma: an International Primary CNS Lymphoma Collaborative Group report. Nancy Doolittle, Lauren Abrey, Tamara Shenkier, Tali Siegal, Jacoline Bromberg, Edward Neuwelt, Carole Soussain, Patrick Johnston, Gerald Illerhaus , David Schiff, Tracy Batchelor, Silvia Montoto, Dale Kraemer, Emanuele Zucca. Blood. 2008 Feb 1;111(3):1085-93. PMID: 17962515
High-dose chemotherapy with autologous stem-cell transplantation and hyperfractionated radiotherapy as first-line treatment of primary CNS lymphoma. Illerhaus G , Marks R, Ihorst G, Guttenberger R, Ostertag C, Derigs G, Frickhofen N, Feuerhake F, Volk B, Finke J. J Clin Oncol.2006 Aug 20;24(24):3865-70. PMID: 16864853
Primary CNS lymphoma in immunocompetent patients from 1989 to 2001: a retrospective analysis of 164 cases uniformly diagnosed by stereotactic biopsy. Feuerhake F, Baumer C, Cyron D, Illerhaus G , Olschewski M, Tilgner J, Ostertag CB, Volk B. Acta Neurochir (Wien). 2006 Aug;148(8):831-8.PMID: 16791439
Meeting Report: Primary Central Nervous System Lymphoma: Standards of Care and Future Perspectives. Herrlinger U, Korfel A, Hebart H, Schlegel U, Plasswilm L, Illerhaus G , Finke J, Kruger W, Montemurro M, Wolf T, Thiel E, Bamberg M, Weller M, Kanz L. Onkologie. 2005 Feb;28(2):109-11. PMID: 15692223
